Abstract: Introduction: The natural history of ocular manifestations is very poor in Behcet's Disease (BD). The lesions progress by successive attacks leading to sever loss of vision or blindness. Aggressive treatments, by the association of cytotoxic drugs and steroids, have dramatically changed the outcome. However, still some ophthalmologists are convinced that the improvement is temporary and in the long run the eyes progress toward blindness. The aim of this study was ...